Relia Tech/Human TWEAK/5 µg/100-111S,Relia Tech,,Relia Tech,reliatech,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Relia Tech/Human TWEAK/5 µg/100-111S

产品编号：100-111S

市场价：¥1500.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>细胞因子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$75.00

品牌： Relia Tech

公司：Receptor Ligand Technologies GmbH

公司分类：

商品介绍

Cat-Nr.	100-111S
Size	5 µg
Price	75 €
Source	E. coli
Formulation	lyophilized
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Length [aa]	154
Molecular Weight	17 kDa
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Biological Activity	Assay #1: The ED50 as determined by the dose-dependent stimulation of IL-8 production by Human PBMC is less than 10 ng/ml. Assay #2: TWEAK weakly induces the death of HT29 cells when cultured in the presence of IFN-γ. The ED50 for this effect is between 30-45 ng/ml.
Species Reactivity	Mouse, Human
Synonyms	TNFSF12; APO3L; DR3LG; TWEAK
Description	TWEAK belongs to the TNF family of ligands and signals through TWEAKR also known as TNFRSF12A. TWEAK is expressed in a variety of tissues, including the adult heart, pancreas, skeletal muscle, small intestine, spleen and peripheral blood lymphocytes. TWEAK has the ability to induce NFkB activation and chemokine secretion, and to exert an apoptotic activity in certain cells, such as HT-29 human adenocarcinoma cells when cultured in the presence of IFN-γ. TWEAK also promotes proliferation and migration of endothelial cells. Recombinant human TWEAK is a soluble 17.0 kDa polypeptide (154 amino acid residues) comprising the TNF homologous region of TWEAK and is generated by proteolytic processing of the full length membrane anchored TWEAK protein.
Protein Sequence	MKGRKTRARR AIAAHYEVHP RPGQDGAQAG VDGTVSGWEE ARINSSSPLR YNRQIGEFIV TRAGLYYLYC QVHFDEGKAV YLKLDLLVDG VLALRCLEEF SATAASSLGP QLRLCQVSGL LALRPGSSLR IRTLPWAHLK AAPFLTYFGL FQVH
Uniprot ID	O43508
Protein RefSeq	NP_003800.1
mRNA RefSeq	NM_003809.2

品牌介绍

ReliaTech

成立于1999年。除其他研究产品外，公司还开发、生产和销售用于血管生成和淋巴管生成研究的高质量研究试剂。

ReliaTech GmbH (short for Receptor Ligand Technologies GmbH) is a post-genomic German biotechnology company founded in 1999. Besides other research products the company develops, produces and sells high quality research reagents for angiogenic and lymphangiogenic research.

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