Relia Tech/Human NOGGIN/5 µg/100-260S,Relia Tech,,Relia Tech,reliatech,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Relia Tech/Human NOGGIN/5 µg/100-260S

产品编号：100-260S

市场价：¥1500.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>细胞因子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$75.00

品牌： Relia Tech

公司：Receptor Ligand Technologies GmbH

公司分类：

商品介绍

Cat-Nr.	100-260S
Size	5 µg
Price	75 €
Source	HEK 293 cells
Formulation	lyophilized
Purity Confirmation	> 95% by SDS-PAGE & HPLC analyses
Length [aa]	206
Molecular Weight	46 kDa
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Biological Activity	Determined by its ability to inhibit 5.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is 2.0-3.0 ng/ml of Noggin.
Species Reactivity	Chicken, Mouse, Human
Synonyms	NOG; SYM1; SYNS1
Description	Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-beta family and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Consequently, Noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of Noggin in mice results in prenatal death and recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing Noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant human Noggin is a 46.2 kDa non-disulfide-linked homodimer consisting of a total of 206 amino acid residues.
Protein Sequence	QHYLHIRPAP SDNLPLVDLI EHPDPIFDPK EKDLNETLLR SLLGGHYDPG FMATSPPEDR PGGGGGAAGG AEDLAELDQL LRQRPSGAMP SEIKGLEFSE GLAQGKKQRL SKKLRRKLQM WLWSQTFCPV LYAWNDLGSR FWPRYVKVGS CFSKRSCSVP EGMVCKPSKS VHLTVLRWRC QRRGGQRCGW IPIQYPIISE CKCSC
Uniprot ID	Q13253
Protein RefSeq	NP_005441
mRNA RefSeq	NM_005450

品牌介绍

ReliaTech

成立于1999年。除其他研究产品外，公司还开发、生产和销售用于血管生成和淋巴管生成研究的高质量研究试剂。

ReliaTech GmbH (short for Receptor Ligand Technologies GmbH) is a post-genomic German biotechnology company founded in 1999. Besides other research products the company develops, produces and sells high quality research reagents for angiogenic and lymphangiogenic research.

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