Cat-Nr. | 101-M71 |
Size | 500 µg |
Price | 250 € |
Category | Monoclonal Antibody |
Isotype | IgG1 |
Species Reactivity | Human |
Formulation | lyophilized from PBS |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
Preparation | Produced in BALB/c mice using recombinant human FGF-5 as the immunizing antigen. This IgG1/K antibody was purified from a Protein A chromatography column. |
Antigen | Recombinant human FGF-5 |
Application | ELISA, N |
Synonyms | FGF5; HBGF-5; Smag-82 |
Description | The FGF family is comprised of at least seven polypeptides that are potent regulators of cell proliferation, differentiation and function. All FGFs have two conserved cysteine residues and share 30-50% sequence homology at the amino acid level. FGF5 was originally identified as a transforming gene by the NIH3T3 focus formation assay using DNA derived from human tumors. FGF5 cDNA encodes a 267 amino acid residue protein with a putative 22 amino acid residue signal peptide. The murine homologue of FGF5 was cloned and found to be 84% homologous to the human protein at the amino acid sequence level. Human and murine FGF5 exhibit cross species activity. In vitro, recombinant human FGF5 is a mitogen for Balb/3T3 fibroblasts and bovine heart endothelial cells. FGF5 was also reported to be a major muscle-derived survival factor for cultured spinal moto-neurons. |
Uniprot ID | P12034 |
Protein RefSeq | NP_004455 |
mRNA RefSeq | NM_004464 |
ReliaTech
成立于1999年。除其他研究产品外,公司还开发、生产和销售用于血管生成和淋巴管生成研究的高质量研究试剂。
ReliaTech GmbH (short for Receptor Ligand Technologies GmbH) is a post-genomic German biotechnology company founded in 1999. Besides other research products the company develops, produces and sells high quality research reagents for angiogenic and lymphangiogenic research.
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