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主营:蛋白纯化试剂,血管和淋巴管研究试剂
℡ 4000-520-616
℡ 4000-520-616
Relia Tech/Mouse Anti-Human CRTAM/100 µg/101-M343
产品编号:101-M343
市  场 价:¥5500.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>单克隆抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$275.00
品      牌: Relia Tech
公司分类:
Relia Tech/Mouse Anti-Human CRTAM/100 µg/101-M343
商品介绍
Cat-Nr.101-M343
Size100 µg
Price275 €
CategoryMonoclonal Antibody
Clone Nr.(#21A9)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant CRTAM extracellular domain.
Antigenhuman recombinant CRTAM extracellular domain
ApplicationWB, FC
SynonymsCRTAM; CD355
DescriptionHuman CRTAM is a 393 amino acid (aa), 80 kDa type I transmembrane glycoprotein. CRTAM is a homodimer on the cell surface but does not show homotypic binding in trans. The high affinity of CRTAM/IGSF4 adhesion allows CRTAM to disrupt IGSF4 homotypic interactions. IGSF4 and T cell receptor co-engagement of CRTAM-expressing CD8+ cells induces increased IFN-gamma or IL-22 production. A role in cancer surveillance through NK cell-mediated rejection of IGSF4-expressing tumors has been proposed. IGSF4 is expressed broadly, including on epithelia, neurons, a subset of tonsillar B cells and a rare splenic T zone-restricted BCDA3+ dendritic cell population which interacts with CRTAM.
Uniprot IDO95727
Protein RefSeqNP_062550.2
mRNA RefSeqNM_019604.2
品牌介绍

ReliaTech


成立于1999年。除其他研究产品外,公司还开发、生产和销售用于血管生成和淋巴管生成研究的高质量研究试剂。


ReliaTech GmbH (short for Receptor Ligand Technologies GmbH) is a post-genomic German biotechnology company founded in 1999. Besides other research products the company develops, produces and sells high quality research reagents for angiogenic and lymphangiogenic research. 


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