Relia Tech/Rat Anti-Mouse EphA3/100 µg/103-M164,Relia Tech,,Relia Tech,reliatech,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Relia Tech/Rat Anti-Mouse EphA3/100 µg/103-M164

产品编号：103-M164

市场价：¥5500.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>单克隆抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$275.00

品牌： Relia Tech

公司：Receptor Ligand Technologies GmbH

公司分类：

商品介绍

Cat-Nr.	103-M164
Size	100 µg
Price	275 €
Category	Monoclonal Antibody
Clone Nr.	(#7C13)
Isotype	IgG2
Species Reactivity	Mouse
Formulation	lyophilized
Buffer	PBS
Reconstitution	Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and Storage	Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Preparation	This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with recombinant mouse EphA3 extracellular domain. IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Antigen	Recombinant mouse EphA3 extracellular domain
Application	WB
Synonyms	Epha3; Hek; Cek4; ETK1; End3; Hek4; Mek4; Tyro4; AW492086
Description	EphA3, also known as Cek4, Mek4, Hek, Tyro4, and Hek4, is a member of the Eph receptor family which binds members of the ephrin ligand family. There are two classes of receptors, designated A and B. Both the A and B class receptors have an extracellular region consisting of a globular domain, a cysteine-rich domain, and two fibronectin type III domains, followed by the transmembrane region and cytoplasmic region. The cytoplasmic region contains a juxtamembrane motif with two tyrosine residues, which are the major autophosphorylation sites, a kinase domain, and a conserved sterile alpha motif (SAM) in the carboxy tail which contains one conserved tyrosine residue. Activation of kinase activity occurs after ligand recognition and binding. EphA3 has been shown to bind ephrinA5, ephrinA2, ephrinA3, ephrinA1, ephrinA4, and ephrinB1. The extracellular domains of mouse and human EphA3 share greater than 96% amino acid identity. Only membranebound or Fcclustered ligands are capable of activating the receptor in vitro. While soluble monomeric ligands bind the receptor, they do not induce receptor autophosphorylation and activation. In vivo, the ligands and receptors display reciprocal expression. It has been found that nearly all receptors and ligands are expressed in developing and adult neural tissue. The Eph/ephrin families also appear to play a role in angiogenesis.
Uniprot ID	Q8BRB1
Protein RefSeq	NP_034270.1
mRNA RefSeq	NM_010140.3

品牌介绍

ReliaTech

成立于1999年。除其他研究产品外，公司还开发、生产和销售用于血管生成和淋巴管生成研究的高质量研究试剂。

ReliaTech GmbH (short for Receptor Ligand Technologies GmbH) is a post-genomic German biotechnology company founded in 1999. Besides other research products the company develops, produces and sells high quality research reagents for angiogenic and lymphangiogenic research.

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