Relia Tech/Mouse Anti-Human MIF/100 µg/101-M571,Relia Tech,,Relia Tech,reliatech,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Relia Tech/Mouse Anti-Human MIF/100 µg/101-M571

产品编号：101-M571

市场价：¥5500.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>单克隆抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$275.00

品牌： Relia Tech

公司：Receptor Ligand Technologies GmbH

公司分类：

商品介绍

Cat-Nr.	101-M571
Size	100 µg
Price	275 €
Category	Monoclonal Antibody
Clone Nr.	(#4E19)
Isotype	IgG1
Species Reactivity	Human
Formulation	lyophilized
Buffer	PBS
Reconstitution	Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and Storage	Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Preparation	This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of MIF.
Antigen	Human recombinant MIF
Application	WB
Synonyms	MIF; GIF; GLIF; MMIF
Description	MIF (or macrophage migration inhibitory factor) was the first lymphokine/cytokine to be recognized in the pregenomics era. Regardless, it is one of the least understood of all inflammatory mediators. Human MIF is a 12.5 kDa, 115 amino acid (aa) nonglycosylated polypeptide that is synthesized without a signal sequence. Secretion occurs nonclassically via an ABCA1 transporter. The initiating Met is removed, leaving Pro as the first amino acid. The molecule consists of two αhelices and six βstrands, four of which form a βsheet. The two remaining βstrands interact with other MIF molecules, creating a trimer. Structure-function studies suggest MIF is bifunctional with segregated topology. The N-and C-termini mediate enzyme activity (in theory). Phenylpyruvate tautomerase activity (enol to keto) has been demonstrated and is dependent upon Pro at position #1. Amino acids 50-65 have also been suggested to contain thiol protein oxidoreductase activity. MIF has proinflammatory cytokine activity centered around aa’s 49-65. On fibroblasts, MIF induces, IL1, IL8, and MMP expression; on macrophages, MIF stimulates NO production and TNF-α release following IFNγ activation. MIF apparently acts through CD74 and CD44, likely in some form of trimeric interaction. Human MIF is active on mouse cells. Human MIF is 90%, 94%, 95%, and 90% aa identical to mouse, bovine, porcine, and rat MIF, respectively.
Uniprot ID	P14174
Protein RefSeq	NP_002406.1
mRNA RefSeq	NM_002415.1

品牌介绍

ReliaTech

成立于1999年。除其他研究产品外，公司还开发、生产和销售用于血管生成和淋巴管生成研究的高质量研究试剂。

ReliaTech GmbH (short for Receptor Ligand Technologies GmbH) is a post-genomic German biotechnology company founded in 1999. Besides other research products the company develops, produces and sells high quality research reagents for angiogenic and lymphangiogenic research.

品牌	货号	名称	规格
ReliaTech	102-P102	Adiponectin	100 µg
ReliaTech	102-P102	Adiponectin	100 µg
ReliaTech	102-P104	CRP	100 µg
ReliaTech	100-442S	FGF-BP-1	5 µg
ReliaTech	100-442	FGF-BP-1	25 µg
ReliaTech	10-437	Follistatin like-protein 1/FSTL1	50 µg
ReliaTech	R20-74	G-CSF	10 µg
ReliaTech	100-444S	GPR15L	5 µg
ReliaTech	100-444	GPR15L	25 µg
ReliaTech	S01-073S	ICOS Fc	10 µg