Cat-Nr. | S01-M44 |
Size | 50 µg |
Price | 285 € |
Source | Insect cells |
Label | His-Tag |
Formulation | lyophilized |
Purity Confirmation | > 95% by SDS-PAGE |
Length [aa] | 712 |
N Terminal Sequence | AMDLILINSL |
Biological Activity | Testing under progress. |
Species Reactivity | Mouse |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. The lyophilized sTIE-2-His is soluble in water and most aqueous buffers and should be reconstituted in PBS or medium to a concentration not lower than 50µg/ml. |
Stability and Storage | Lyophilized samples are stable for greater than six months at -20°C to -70°C. Reconstituted sTIE-2-His should be stored in working aliquots at -20°C. |
Synonyms | Angiopoietin-1 receptor; Endothelial tyrosine kinase; HYK; STK1; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; p140 TEK; CD202b; Tek; Hyk; Tie2; AA517024 |
Description | Recombinant mouse soluble TIE-2 was fused with a 6x His-tag at the C-terminus. The soluble receptor protein consists of the full extracellular domain (Ala23-Ala737). Mouse sTIE-2 monomer has a calculated molecular mass of approximately 79,86 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 95 kDa protein in SDS-PAGE under reducing conditions. TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. |
Protein Sequence | AMDLILINSLPLVSDAETLTCIASGWHPHEPITIGRDFEALMNQHQDPLEVTQDVTREWAKKVVWKREKASKINGAYCEGRVRGQAIRIRTMKMRQQASFLPATLTMTVDRGDNVNISFKKVLIKEEDAVIYKNGSIHSVPRHEVPDILEVHLPHAQPQDAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPDCRPCTTCKNNGVCHEDTGECICPPGFMGRTCEKACEPHTFGRTCKERCSGPEGCKSYVFCPDPYGCSCATGWRGLQCNEACPSGYYGPDCKLRCHCTNEEICDRFQGCLCSQGWQGLQCKEGRPRMTPQIEDLPDHIEVNSGKFNPICKASGWPLPTSEEMTLVKPDGTVLQPNDFNYDRFSVAIFTVNRVLPPDSGVWVCSVNTVAGMVEKPFNISVKVLPEPLHAPNVIDTGHNFIINISSEPYFGDGPIKSKKLFYKPVNQAWKYIEVTNEIFTLNYLEPRTDYELCVQLARPEGGEGHPGPVRRFTTASIGLPPPRGLSLLPKSQTALNLTWQPIFTNSEDEFYVEVERRSQTTSDQQNIKVPGNLTSVLLSNLVPREQYTVRARVNTKAQGEWSEELRAWTLSDILPPQENIKISNITDSTAMVSWTIVDGYSISSIIIRYKVQGKNEDQHIDVKIKNATVTQYQLKGEPETTYHVDIFAENNIGSSNPAFSHELRTLPHSPASATRHHHHHH |
Uniprot ID | Q02858 |
Protein RefSeq | NP_038718.2 |
mRNA RefSeq | NM_013690.2 |
ReliaTech
成立于1999年。除其他研究产品外,公司还开发、生产和销售用于血管生成和淋巴管生成研究的高质量研究试剂。
ReliaTech GmbH (short for Receptor Ligand Technologies GmbH) is a post-genomic German biotechnology company founded in 1999. Besides other research products the company develops, produces and sells high quality research reagents for angiogenic and lymphangiogenic research.
品牌 | 货号 | 名称 | 规格 |
ReliaTech | 102-P102 | Adiponectin | 100 µg |
ReliaTech | 102-P102 | Adiponectin | 100 µg |
ReliaTech | 102-P104 | CRP | 100 µg |
ReliaTech | 100-442S | FGF-BP-1 | 5 µg |
ReliaTech | 100-442 | FGF-BP-1 | 25 µg |
ReliaTech | 10-437 | Follistatin like-protein 1/FSTL1 | 50 µg |
ReliaTech | R20-74 | G-CSF | 10 µg |
ReliaTech | 100-444S | GPR15L | 5 µg |
ReliaTech | 100-444 | GPR15L | 25 µg |
ReliaTech | S01-073S | ICOS Fc | 10 µg |